Thursday, April 23, 2009

Scientific misconduct by Mak, Pillus and Ideker

Taking credit or attempting to do so for the work of others is an act of scientific misconduct. Failure to appropriately credit prior discoverers, commonly termed plagiarism, is not an unknown phenomenon in science (Please see wikipedia for definitions of plagiarism). One would believe that the existence of repositories like Pubmed along with the associated search tool as well as "the universal search tool" Google should minimize such events. However, this does not seem to be the case .
It came to our attention that Mak, Pillus and Ideker have published an article which, in our opinion, constitutes scientific misconduct in relation to our previously published work.

The work in question published in April 2009.

Our earlier study regarding transcription factor-telomere interactions and its implication for gene regulation published in October 2006 may be accessed here. Using ChIP-chip data we discovered that TGs in the subtelomeric regions had an unusually large number of binding events (i.e. incoming connections in then transcriptional network >13) with functionally diverse TFs. We proposed that this might result from TF–telomere interactions being captured in the ChIP-chip experiments owing to either the telomeres looping back and interacting with chromatin complexes on internal chromosomal sites or because of the interaction of chromosome ends with diverse TFs assembled at the inner nuclear envelope. Further results supporting this finding were subsequently published in July 2008 here.

Authors claiming to perform "bioinformatics" will probably benefit from learning to use Pubmed or even Google prior to rushing to publish: